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A Phase 2, Double-Blind, Placebo-Controlled, Dose Escalation Study to Assess the Safety, Efficacy, and Pharmacokinetics of ISIS 301012 [mipomersen sodium] as Add-on Therapy in Heterozygous Familial Hypercholesterolemia Subjects.

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A Phase 2, Double-Blind, Placebo-Controlled, Dose Escalation Study to Assess the Safety, Efficacy, and Pharmacokinetics of ISIS 301012 [mipomersen sodium] as Add-on Therapy in Heterozygous Familial Hypercholesterolemia Subjects.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Aug 2016

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At a glance

  • Drugs Mipomersen (Primary)
  • Indications Hyperlipoproteinaemia type IIa
  • Focus Therapeutic Use
  • Sponsors Genzyme Corporation

    • Most Recent Events

    • 15 May 2010 Results published in The American journal of cardiology.
    • 25 Jun 2008 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 10 Oct 2007 Drug named changed from ISIS 301012 to mipomersen sodium (INN).

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