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A phase I/II study of the combination of 5-azacytidine [azacitidine] with valproic acid and all-trans retinoic acid [tretinoin] in patients with high risk myelodysplastic syndrome and acute myelogenous leukaemia.

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Trial Profile

A phase I/II study of the combination of 5-azacytidine [azacitidine] with valproic acid and all-trans retinoic acid [tretinoin] in patients with high risk myelodysplastic syndrome and acute myelogenous leukaemia.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Azacitidine (Primary) ; Tretinoin; Valproic acid
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 14 Jun 2012 Actual patient number changed from 55 to 34 as reported by ClinicalTrials.gov. (NCT00326170).
    • 14 Jun 2012 Actual patient number changed from 55 to 34 as reported by ClinicalTrials.gov. (NCT00326170).
    • 11 Aug 2009 Actual end date (1 Dec 2007) added as reported by ClinicalTrials.gov.

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