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A Phase 1B, Sequential Cohort, Dose Escalation Trial to Determine the Safety, Tolerability and Maximum Tolerated Dose of Oral AP23573 in Combination With Doxorubicin.

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Trial Profile

A Phase 1B, Sequential Cohort, Dose Escalation Trial to Determine the Safety, Tolerability and Maximum Tolerated Dose of Oral AP23573 in Combination With Doxorubicin.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 May 2022

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At a glance

  • Drugs Ridaforolimus (Primary) ; Doxorubicin
  • Indications Breast cancer; Endometrial cancer; Ovarian cancer; Sarcoma
  • Focus Adverse reactions
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 09 Jun 2009 Actual end date (Oct 2008) added as reported by ClinicalTrials.gov.
    • 12 May 2009 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 22 Jan 2008 The expected completion date for this trial is now 1 Dec 2008 as reported by ClinicalTrials.gov.

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