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A Phase I Trial and Pharmacokinetic Study of Talabostat (PT-100, Val-Boro-Pro) in Combination With Temozolomide or Carboplatin in Pediatric Patients With Relapsed or Refractory Solid Tumors Including Brain Tumors.

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Trial Profile

A Phase I Trial and Pharmacokinetic Study of Talabostat (PT-100, Val-Boro-Pro) in Combination With Temozolomide or Carboplatin in Pediatric Patients With Relapsed or Refractory Solid Tumors Including Brain Tumors.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Carboplatin (Primary) ; Talabostat (Primary) ; Temozolomide (Primary)
  • Indications Brain cancer; Ewing's sarcoma; Germ cell and embryonal neoplasms; Germ cell cancer; Hepatic tumours; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Soft tissue sarcoma; Wilms' tumour
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 06 Apr 2010 Actual end date (1 Feb 2010) added as reported by ClinicalTrials.gov record.
    • 06 Apr 2010 Actual end date (1 Feb 2010) added as reported by ClinicalTrials.gov record.
    • 06 Apr 2010 Status changed from suspended to completed as reported by ClinicalTrials.gov record.

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