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Effects of candesartan cilexetil (Candesartan) on diabetic retinopathy in type 1 diabetic patients without retinopathy

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Trial Profile

Effects of candesartan cilexetil (Candesartan) on diabetic retinopathy in type 1 diabetic patients without retinopathy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Jun 2014

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At a glance

  • Drugs Candesartan cilexetil (Primary)
  • Indications Diabetic nephropathies; Diabetic retinopathy; Proteinuria
  • Focus Registrational; Therapeutic Use
  • Acronyms DIRECT; DIRECT-Prevent-1
  • Sponsors AstraZeneca

    • Most Recent Events

    • 07 Jul 2009 Results of a prespecified pooled analysis of the three DIRECT trials (DIRECT-Renal) published in Annals of Internal Medicine.
    • 26 Sep 2008 Results have been published in the Lancet.
    • 11 Sep 2008 Primary endpoint 'Diabetic complications occurrence' has not been met, as reported in a Takeda media release.

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