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A prospective, randomized, open, multicentre phase III study to assess the efficacy of secondary adjuvant endocrine anastrozole therapy for 2 further yrs vs 5 further yrs in patients with HR +Ve breast cancer after 5-yr primary adjuvant endocrine therapy

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A prospective, randomized, open, multicentre phase III study to assess the efficacy of secondary adjuvant endocrine anastrozole therapy for 2 further yrs vs 5 further yrs in patients with HR +Ve breast cancer after 5-yr primary adjuvant endocrine therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Anastrozole (Primary)
  • Indications Advanced breast cancer; Carcinoma; Early breast cancer
  • Focus Therapeutic Use
  • Acronyms SALSA
  • Sponsors AstraZeneca

    • Most Recent Events

    • 29 Jul 2021 Results published in the New England Journal of Medicine
    • 12 Mar 2018 Status changed from active, no longer recruiting to completed.
    • 09 Dec 2017 Primary endpoint (Assessment of the effect in terms of DFS of 2 further years of anastrozole treatment vs further 5 years of adjuvant anastrozole treatment, following 5 years of adjuvant endocrine treatment) has not been met, as per results presented at the 40th Annual San Antonio Breast Cancer Symposium.

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