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A Prospective, Randomized, Double-blind, Stratified, Multi-center, 2-arm Trial of the Continued Efficacy and Safety of Zoledronic Acid (Every 4 Weeks vs. Every 12 Weeks) in in the 2nd Year of Treatment in Patients With Documented Bone Metastases From Breast Cancer

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A Prospective, Randomized, Double-blind, Stratified, Multi-center, 2-arm Trial of the Continued Efficacy and Safety of Zoledronic Acid (Every 4 Weeks vs. Every 12 Weeks) in in the 2nd Year of Treatment in Patients With Documented Bone Metastases From Breast Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Zoledronic acid (Primary)
  • Indications Advanced breast cancer; Cancer metastases
  • Focus Therapeutic Use
  • Acronyms OPTIMIZE-2
  • Sponsors Novartis

    • Most Recent Events

    • 02 Jun 2015 Results assessing bone saturation with zoledronic acid presented at the 51st Annual Meeting of the American Society of Clinical Oncology.
    • 08 Jul 2014 Treatment arms changed from 3 to 2, end point got changed and official title got changed.
    • 01 Jul 2013 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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