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Biomarkers for Rapid Identification of Treatment Effectiveness in Major Depression (BRITE-MD), a prospective, randomized, multi-center study to determine the efficacy of selected EEG and genotype biomarkers for predicting response to antidepressant therapy with escitalopram, bupropion XL, or a combination treatment regimen.

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Trial Profile

Biomarkers for Rapid Identification of Treatment Effectiveness in Major Depression (BRITE-MD), a prospective, randomized, multi-center study to determine the efficacy of selected EEG and genotype biomarkers for predicting response to antidepressant therapy with escitalopram, bupropion XL, or a combination treatment regimen.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Bupropion (Primary) ; Escitalopram (Primary)
  • Indications Depression; Major depressive disorder
  • Focus Biomarker; Therapeutic Use
  • Acronyms BRITE-MD
  • Most Recent Events

    • 07 Mar 2012 Biomarkers information updated
    • 06 Apr 2010 Actual patient number (375), additional lead trial centre added as reported by ClinicalTrials.gov.
    • 06 Apr 2010 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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