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A Phase I Study of Vorinostat (Suberoylanilide Hydroxamic Acid [SAHA]) in Combination With Temozolomide in Patients With Malignant Gliomas

Trial Profile

A Phase I Study of Vorinostat (Suberoylanilide Hydroxamic Acid [SAHA]) in Combination With Temozolomide in Patients With Malignant Gliomas

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Sep 2023

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At a glance

  • Drugs Temozolomide (Primary) ; Vorinostat (Primary)
  • Indications Anaplastic astrocytoma; Astrocytoma; Glioblastoma; Glioma; Gliosarcoma; Oligodendroglioma
  • Focus Adverse reactions
  • Most Recent Events

    • 25 Apr 2023 Planned End Date changed from 11 Apr 2023 to 11 Apr 2024.
    • 12 Apr 2022 Planned End Date changed from 1 Aug 2012 to 11 Apr 2023.
    • 27 Jun 2011 Planned end date changed from 1 Aug 2007 to 1 Aug 2012 as reported by ClinicalTrials.gov.
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