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A Phase I Dose-finding and Pharmacokinetic Study of Intravenous RTA 744 Injection in Patients With Recurrent or Refractory Anaplastic Astrocytoma (AA), Anaplastic Oligodendroglioma (AO), Anaplastic Mixed Oligo-astrocytoma (AOA), Glioblastoma Multiforme (GBM) or Gliosarcoma (GS), With or Without Concurrent Treatment With Enzyme-inducing Anticonvulsant Therapy

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Trial Profile

A Phase I Dose-finding and Pharmacokinetic Study of Intravenous RTA 744 Injection in Patients With Recurrent or Refractory Anaplastic Astrocytoma (AA), Anaplastic Oligodendroglioma (AO), Anaplastic Mixed Oligo-astrocytoma (AOA), Glioblastoma Multiforme (GBM) or Gliosarcoma (GS), With or Without Concurrent Treatment With Enzyme-inducing Anticonvulsant Therapy

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Feb 2024

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At a glance

  • Drugs Berubicin (Primary)
  • Indications Anaplastic astrocytoma; Glioblastoma; Glioma; Gliosarcoma; Oligodendroglioma
  • Focus Adverse reactions
  • Sponsors Reata Pharmaceuticals

    • Most Recent Events

    • 17 Dec 2020 According to an CNS Pharmaceuticals media release, one patient experienced a durable complete response and remains cancer-free as of Feb. 20, 2020.
    • 17 Dec 2020 Results presented in the CNS Pharmaceuticals Media Release.
    • 03 Sep 2020 According to an CNS Pharmaceuticals media release, the company has completed Phase 1 Clinical Study Report which is ready for publication.

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