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A randomized phase 2 trial of double-blind, placebo controlled AMG 706 [motesanib] in combination with paclitaxel, or open-label bevacizumab in combination with paclitaxel, as first line therapy in women with HER2 negative locally recurrent or metastatic breast cancer

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A randomized phase 2 trial of double-blind, placebo controlled AMG 706 [motesanib] in combination with paclitaxel, or open-label bevacizumab in combination with paclitaxel, as first line therapy in women with HER2 negative locally recurrent or metastatic breast cancer

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Motesanib (Primary) ; Bevacizumab; Paclitaxel
  • Indications Advanced breast cancer
  • Focus Therapeutic Use
  • Sponsors Amgen

    • Most Recent Events

    • 01 Aug 2012 Status changed from active, no longer recruiting to discontinued as reported by ClinicalTrials.gov.
    • 09 Jul 2011 Additional lead trial center identified as reported by Australian New Zealand Clinical Trials Registry.
    • 09 Jul 2011 New source identified and integrated (Australian New Zealand Clinical Trials Registry)

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