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2-Weekly CHOP Chemotherapy With Dose-Dense Rituximab for the Treatment of Patients Aged 61 to 80 Years With Aggressive CD-20 Positive B-Cell Lymphomas: A Phase-II/Pharmacokinetic Study (CHOP-R-ESC)

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Trial Profile

2-Weekly CHOP Chemotherapy With Dose-Dense Rituximab for the Treatment of Patients Aged 61 to 80 Years With Aggressive CD-20 Positive B-Cell Lymphomas: A Phase-II/Pharmacokinetic Study (CHOP-R-ESC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Rituximab (Primary) ; Cyclophosphamide; Doxorubicin; Pegfilgrastim; Prednisone; Vincristine
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions; Pharmacokinetics
  • Acronyms SEXIE-R-CHOP-14
  • Sponsors Roche
  • Most Recent Events

    • 01 Apr 2021 Results analyzing the influence of age in pts > 60 years receiving the R-CHOP-14 regimen from RICOVER-60 and consecutive phase-II CHOP-R-ESC trials: DENSE-R-, SMARTE-R-, and SEXIE-R-CHOP-14, published in the Annals of Hematology.
    • 24 Nov 2015 Status changed from recruiting to completed as reported by ClinicalTrials.gov record.
    • 03 Jun 2014 Results presented at the 50th Annual Meeting of the American Society of Clinical Oncology.

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