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A phase I study to determine the safety, pharmacokinetics and pharmacodynamics of BMS-582664 [brivanib] in combination with 5-fluorouracil/leucovorin [folinic acid] and irinotecan or oxaliplatin for patients with advanced or metastatic cancer

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Trial Profile

A phase I study to determine the safety, pharmacokinetics and pharmacodynamics of BMS-582664 [brivanib] in combination with 5-fluorouracil/leucovorin [folinic acid] and irinotecan or oxaliplatin for patients with advanced or metastatic cancer

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 06 Mar 2007

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At a glance

  • Drugs Brivanib alaninate (Primary) ; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Gastrointestinal cancer
  • Focus Adverse reactions
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 06 Mar 2007 Status changed from recruiting to discontinued.
    • 07 Aug 2006 New trial record.
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