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Phase 1 study of the evaluation of dihydropyrimidine dehydrogenase (DPD), uridine phosphorylase (UP), orotate phosphoribosyl transferase (OPRT), and thymidine phosphorylase (TP) activity in tissue resected from subjects undergoing planned resection of primary or metastatic colorectal cancer and liver biopsy, or planned hepatic resection, following administration of oral ADH300004 [eniluracil] (Adherex Protocol Number AHX-03-101)

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Trial Profile

Phase 1 study of the evaluation of dihydropyrimidine dehydrogenase (DPD), uridine phosphorylase (UP), orotate phosphoribosyl transferase (OPRT), and thymidine phosphorylase (TP) activity in tissue resected from subjects undergoing planned resection of primary or metastatic colorectal cancer and liver biopsy, or planned hepatic resection, following administration of oral ADH300004 [eniluracil] (Adherex Protocol Number AHX-03-101)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Eniluracil (Primary)
  • Indications Colorectal cancer
  • Focus Pharmacodynamics
  • Sponsors Adherex Technologies

    • Most Recent Events

    • 18 Jan 2007 Status changed from recruiting to completed.
    • 18 Aug 2006 New trial record.
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