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A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin Versus Concurrent Accelerated Radiation, Cisplatin, and Cetuximab (C225) [Followed by Surgery for Selected Patients] for Stage III and IV Head and Neck Carcinomas

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A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin Versus Concurrent Accelerated Radiation, Cisplatin, and Cetuximab (C225) [Followed by Surgery for Selected Patients] for Stage III and IV Head and Neck Carcinomas

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Jul 2023

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At a glance

  • Drugs Cetuximab (Primary) ; Cisplatin
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Oropharyngeal cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use

    • Most Recent Events

    • 01 Jul 2023 Primary endpoint has not been met. (Progression-free Survival (PFS) (3-year Rate Reported))
    • 01 Jul 2023 Results published in the International Journal of Radiation Oncology, Biology, Physics
    • 23 May 2022 Status changed from active, no longer recruiting to completed.

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