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Evaluation of Fludarabine, Busulfan and Alemtuzumab as a Reduced Toxicity Ablative Bone Marrow Stem Cell Transplant Regimen for Children With Stem Cell Defects, Marrow Failure Syndromes, or Myelodysplastic Syndrome (MDS)/Leukemia

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Trial Profile

Evaluation of Fludarabine, Busulfan and Alemtuzumab as a Reduced Toxicity Ablative Bone Marrow Stem Cell Transplant Regimen for Children With Stem Cell Defects, Marrow Failure Syndromes, or Myelodysplastic Syndrome (MDS)/Leukemia

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Alemtuzumab; Busulfan; Ciclosporin; Filgrastim; Fludarabine; Methotrexate; Methylprednisolone
  • Indications Graft-versus-host disease; Myelodysplastic syndromes; Myeloid leukaemia
  • Focus Therapeutic Use

    • Most Recent Events

    • 28 Sep 2017 Biomarkers information updated
    • 25 Oct 2008 1 Dec 2010 added as the planned end date, based on information from ClinicalTrials.gov.
    • 11 Sep 2006 New trial record.

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