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A Randomized Dose Ranging Study of Hexadecasaccharide Including Active Control, in Patients With Unstable Angina or Non-ST-Segment Elevation Myocardial Infarction Scheduled to Undergo Percutaneous Coronary Intervention (SHINE)

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Trial Profile

A Randomized Dose Ranging Study of Hexadecasaccharide Including Active Control, in Patients With Unstable Angina or Non-ST-Segment Elevation Myocardial Infarction Scheduled to Undergo Percutaneous Coronary Intervention (SHINE)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Apr 2022

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At a glance

  • Drugs SR 123781 (Primary) ; SR 123781 (Primary) ; Abciximab; Heparin
  • Indications Acute coronary syndromes; Embolism and thrombosis; Myocardial infarction; Unstable angina pectoris
  • Focus Therapeutic Use
  • Acronyms SHINE
  • Sponsors Sanofi

    • Most Recent Events

    • 11 Mar 2008 According to results presented at the ACC meeting, the primary outcome was met; however, treatment with the three lowest dosages of SR123781 was discontinued early due to a high incidence of catheter-related thrombosis.
    • 11 Mar 2008 Results were presented at the 57th Annual Scientific Session of the American College of Cardiology (ACC).
    • 02 Aug 2007 Status changed from in progress to completed.

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