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American-Australian-African Trial With DronedarONe In Atrial Fibrillation or Flutter Patients for the Maintenance of Sinus Rhythm (ADONIS)

Trial Profile

American-Australian-African Trial With DronedarONe In Atrial Fibrillation or Flutter Patients for the Maintenance of Sinus Rhythm (ADONIS)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 12 Jul 2022

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At a glance

  • Drugs Dronedarone (Primary)
  • Indications Atrial fibrillation; Atrial flutter
  • Focus Registrational; Therapeutic Use
  • Acronyms ADONIS
  • Sponsors Sanofi

Most Recent Events

  • 01 Jul 2022 Results of sub-analysis of the ATHENA and EURIDIS/ADONIS studies published in the Journal of Diabetes and its Complications
  • 15 Jan 2022 Results (n=1795) of post hoc analysis of pooled data from two (EURIDIS and ADONIS) assessing the patient characteristics as predictors of dronedarone trough concentrations and characterized the relationship of the trough concentrations of dronedarone with its efficacy and safety, published in the Clinical Cardiology.
  • 12 Jan 2022 Results (n=1229) of post hoc, pooled analysis from NCT00259428 and NCT00259376 assessing safety and efficacy of dronedarone versus placebo in patients with atrial fibrillation stratified according to renal function, published in the Clinical Cardiology

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