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A phase 2, multi-centre, randomised, double blind, placebo controlled study evaluating the efficacy, safety and pharmacokinetics of two doses of a candidate disease modifying anti-rheumatic drug (DMARD), (SMP-114 120 mg and 240 mg once daily), administered in combination with ongoing methotrexate treatment in patients with active rheumatoid arthritis

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Trial Profile

A phase 2, multi-centre, randomised, double blind, placebo controlled study evaluating the efficacy, safety and pharmacokinetics of two doses of a candidate disease modifying anti-rheumatic drug (DMARD), (SMP-114 120 mg and 240 mg once daily), administered in combination with ongoing methotrexate treatment in patients with active rheumatoid arthritis

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 12 Sep 2019

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At a glance

  • Drugs Rimacalib (Primary) ; Methotrexate
  • Indications Rheumatoid arthritis
  • Focus Therapeutic Use
  • Acronyms ASPECTS
  • Sponsors Sumitomo Pharma
  • Most Recent Events

    • 10 Sep 2019 Planned End Date changed from 1 Jun 2008 to 21 Jul 2008.
    • 29 Jan 2015 Status changed from discontinued to completed as per ISRCTN: Current Controlled Trials.
    • 22 Aug 2007 Status changed from recruiting to in progress.

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