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Prevention of cerebrovascular and cardiovascular Events of ischaemic origin with teRutroban in patients with a history oF ischaemic strOke or tRansiet ischaeMic attack. The PERFORM Study. An international, randomised, double-blind, two parallel group study comparing terutroban 30 mg o.d. versus aspirin 100 mg o.d. administered orally for 3-year mean duration (event driven trial).

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Trial Profile

Prevention of cerebrovascular and cardiovascular Events of ischaemic origin with teRutroban in patients with a history oF ischaemic strOke or tRansiet ischaeMic attack. The PERFORM Study. An international, randomised, double-blind, two parallel group study comparing terutroban 30 mg o.d. versus aspirin 100 mg o.d. administered orally for 3-year mean duration (event driven trial).

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 05 Aug 2019

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At a glance

  • Drugs Aspirin (Primary) ; Terutroban sodium (Primary)
  • Indications Cardiovascular disorders; Embolism and thrombosis; Stroke; Transient ischaemic attacks
  • Focus Pharmacogenomic; Registrational; Therapeutic Use
  • Acronyms PERFORM
  • Most Recent Events

    • 30 May 2011 Results published in the Lancet.
    • 03 Mar 2011 New source identified and integrated (United Kingdom Clinical Research Network, 9869).
    • 29 Sep 2010 Status changed from active, no longer recruiting to discontinued.

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