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A multicenter, randomized placebo controlled pilot microCT study to estimate the effect of treatment with denosumab (AMG 162) and alendronate sodium in postmenopausal women with low bone mineral density.

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Trial Profile

A multicenter, randomized placebo controlled pilot microCT study to estimate the effect of treatment with denosumab (AMG 162) and alendronate sodium in postmenopausal women with low bone mineral density.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 Mar 2022

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At a glance

  • Drugs Denosumab (Primary) ; Alendronic acid
  • Indications Bone resorption; Fracture; Postmenopausal osteoporosis
  • Focus Therapeutic Use
  • Sponsors Amgen

    • Most Recent Events

    • 02 Apr 2014 Results comparing trabecular bone score and bone mineral density presented at the 2014 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
    • 08 Oct 2013 Results assessing bone measures at the lumbar spine, including the trabecular bone score, presented at the 35th Annual Meeting of the American Society for Bone and Mineral Research.
    • 16 Oct 2012 Results assessing effects of treatment on trabecular bone volume fraction and intracortical porosity presented at the 34th Annual Meeting of the American Society for Bone and Mineral Research.

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