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A Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX4032 in Patients With Solid Tumors

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Trial Profile

A Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX4032 in Patients With Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Vemurafenib (Primary)
  • Indications Colorectal cancer; Malignant melanoma; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Plexxikon

    • Most Recent Events

    • 18 Aug 2017 Status changed from active, no longer recruiting to completed.
    • 12 Oct 2015 Results of extension cohort (n=21; assessing objective tumour response in patients with colorectal cancer and BRAF + V600E mutations) published in the Journal of Clinical Oncology
    • 03 May 2015 Planned End Date changed from 1 Dec 2014 to 1 Sep 2015, as reported by ClinicalTrials.gov.

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