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A Multicenter, Randomized, Parallel-Group, Placebo-Controlled, Double-Blind Study With In-House Blinding to Determine the Effect of 156 Weeks of Treatment With MK0966 on the Recurrence of Neoplastic Polyps of the Large Bowel in Patients With a History of Colorectal Adenomas.

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A Multicenter, Randomized, Parallel-Group, Placebo-Controlled, Double-Blind Study With In-House Blinding to Determine the Effect of 156 Weeks of Treatment With MK0966 on the Recurrence of Neoplastic Polyps of the Large Bowel in Patients With a History of Colorectal Adenomas.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 May 2022

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At a glance

  • Drugs Rofecoxib (Primary)
  • Indications Colorectal cancer; Intestinal polyps; Polyps
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms APPROVe
  • Sponsors Merck & Co; Merck Sharp & Dohme

    • Most Recent Events

    • 12 May 2009 Additional trial identifier MK0966-122 identified as reported by ClinicalTrials.gov.
    • 15 Nov 2008 Cardiovascular safety results published in The Lancet.
    • 11 Oct 2006 New trial record.

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