Protocol of Herceptin Adjuvant With Reduced Exposure, a Randomised Comparison of 6 Months vs 12 Months in All Women Receiving Adjuvant Herceptin [PHARE].

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

Drugs Trastuzumab (Primary)
Indications Adenocarcinoma; Early breast cancer; HER2 positive breast cancer
Focus Therapeutic Use
Acronyms PHARE

01 Aug 2017 Results (n=5502) assessing sequential versus concomitant administration of adjuvant trastuzumab in HER2-positive breast cancer using patient data from NCT00381901 and SIGNAL trials published in the European Journal of Cancer
11 Oct 2016 Results evaluating the impact of HER expression levels in the PHARE/SIGNAL cohort (n=5474; HER2+) presented at the 41st European Society for Medical Oncology Congress
11 Oct 2016 Results of sequential vs concomitant incorporation of trastuzumab with chemotherapy in the PHARE/SIGNAL cohort (n=5502; HER2+) presented at the 41st European Society for Medical Oncology Congress

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