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A double-blind, placebo-controlled, randomized, multi-center phase II trial to assess the efficacy of sorafenib added to standard primary therapy in elderly patients with newly diagnosed AML [acute myeloid leukaemia].

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Trial Profile

A double-blind, placebo-controlled, randomized, multi-center phase II trial to assess the efficacy of sorafenib added to standard primary therapy in elderly patients with newly diagnosed AML [acute myeloid leukaemia].

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Sorafenib (Primary) ; Antineoplastics; Cytarabine; Daunorubicin
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use

    • Most Recent Events

    • 29 Jul 2013 Primary endpoint 'Event-free-survival-duration' has not been met.
    • 29 Jul 2013 Results published in the Journal of Clinical Oncology.
    • 12 Jul 2011 New source identified and integrated (European Clinical Trials Database; EudraCT2005-005966-35).

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