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A prospective, randomized, open-label, pilot study to compare the effect on carotid atherosclerosis of a tacrolimus-based regimen with conversion from a tacrolimus- to a sirolimus-based regimen at 3-4 months post-transplant in de novo renal transplant recipients.

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A prospective, randomized, open-label, pilot study to compare the effect on carotid atherosclerosis of a tacrolimus-based regimen with conversion from a tacrolimus- to a sirolimus-based regimen at 3-4 months post-transplant in de novo renal transplant recipients.

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Sirolimus (Primary) ; Mycophenolate mofetil; Mycophenolate sodium; Prednisone; Tacrolimus
  • Indications Renal transplant rejection
  • Focus Biomarker; Pharmacodynamics
  • Sponsors Pfizer

    • Most Recent Events

    • 23 May 2012 Actual initiation date changed from Mar 2006 to Apr 2006 as reported by ClinicalTrials.gov.
    • 23 May 2012 Planned end date changed from 1 Mar 2013 to 1 Jan 2012 as reported by ClinicalTrials.gov.
    • 23 May 2012 Status changed from active, no longer recruiting to discontinued as reported by ClinicalTrials.gov.

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