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Adjuvant Treatment of Fully Resected Stage III Colon Cancer With FOLFOX-4 Versus FOLFOX-4 Plus Cetuximab

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Trial Profile

Adjuvant Treatment of Fully Resected Stage III Colon Cancer With FOLFOX-4 Versus FOLFOX-4 Plus Cetuximab

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 Oct 2023

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At a glance

  • Drugs Cetuximab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Colon cancer
  • Focus Therapeutic Use
  • Acronyms PETACC-8

    • Most Recent Events

    • 09 Sep 2023 Results of post hoc pooled analysis (n=4548) from the PETACC-8 and International Duration Evaluation of Adjuvant chemotherapy (IDEA)-France trials looking at TTR depending on BRAF V6000E, RAS, and MMR status, and the impact of TTR on survival in general and specifically in these molecular subgroups, published in the European Journal of Cancer.
    • 16 Jan 2020 Results (n=6501) of pooled analysis of six clinical trials (NCT00079274; NCT00096278; NCT00004931; NCT00275210; NCT00265811; NCT00112918) examining the change of outcomes over 10-year period in patients with stage 3 colon cancer who were treated with fluorouracil, leucovorin, and oxaliplatin in the ACCENT database, published in the Annals of Oncology.
    • 09 Jun 2019 Trial has been completed in UK.

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