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Phase II single arm trial of VEGF Trap [aflibercept] in patients with recurrent temozolomide-resistant malignant gliomas

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Trial Profile

Phase II single arm trial of VEGF Trap [aflibercept] in patients with recurrent temozolomide-resistant malignant gliomas

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Aflibercept (Primary)
  • Indications Anaplastic astrocytoma; Astrocytoma; Glioblastoma; Glioma; Gliosarcoma; Oligodendroglioma
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 27 Jun 2017 Converging evidence from 5 seperate phase II trials (NCT00035656, NCT00345163, NCT00704288, NCT00369590 and NTR1929) results published in the Clinical cancer research: an official journal of the American Association for Cancer Research
    • 08 Apr 2013 Status changed from completed to active, no longer recruiting as reported by ClinicalTrials.gov.
    • 01 May 2012 Actual end date (Apr 2011) added as reported by ClinicalTrials.gov.

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