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A phase 2A, randomized, controlled, double-blind, multicenter study to evaluate the safety, tolerability, and effect on body weight of recombinant-methionyl human leptin [metreleptin; r-metHuLeptin] administered in conjunction with pramlintide in overweight and obese subjects.

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A phase 2A, randomized, controlled, double-blind, multicenter study to evaluate the safety, tolerability, and effect on body weight of recombinant-methionyl human leptin [metreleptin; r-metHuLeptin] administered in conjunction with pramlintide in overweight and obese subjects.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Metreleptin (Primary) ; Pramlintide (Primary)
  • Indications Obesity; Overweight
  • Focus Therapeutic Use
  • Sponsors Bristol-Myers Squibb

    • Most Recent Events

    • 27 Feb 2014 The primary endpoint and treatment arms (from 3 to 4) has been changed.
    • 01 Sep 2009 Results were published in Obesity.
    • 07 Sep 2008 Results presented at the 44th Annual Meeting of the European Association for the Study of Diabetes

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