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An International, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Active-Controlled Study of the Efficacy and Safety of Sustained-Release Quetiapine Fumarate (Seroquel SR) in the Treatment of Generalized Anxiety Disorder (SILVER)

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Trial Profile

An International, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Active-Controlled Study of the Efficacy and Safety of Sustained-Release Quetiapine Fumarate (Seroquel SR) in the Treatment of Generalized Anxiety Disorder (SILVER)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 29 Dec 2021

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At a glance

  • Drugs Quetiapine (Primary) ; Paroxetine
  • Indications Generalised anxiety disorder
  • Focus Registrational; Therapeutic Use
  • Acronyms SILVER
  • Sponsors AstraZeneca

    • Most Recent Events

    • 31 Oct 2012 Planned number of patients changed from 800 to 805 as reported by European Clinical Trials Database record.
    • 06 Dec 2011 Results from a pooled analysis published in the Human Psychopharmacology: Clinical and Experimental.
    • 28 Jun 2009 Planned pooled analysis of data from the GOLD, SILVER and TITANIUM trials presented at the 9th World Congress of Biological Psychiatry.

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