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A randomized phase III study in previously untreated patients with biological high-risk CLL [chronic lymphocytic leukaemia]: fludarabine and cyclophosphamide (FC) versus FC and low-dose alemtuzumab

Trial Profile

A randomized phase III study in previously untreated patients with biological high-risk CLL [chronic lymphocytic leukaemia]: fludarabine and cyclophosphamide (FC) versus FC and low-dose alemtuzumab

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 17 Aug 2023

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At a glance

  • Drugs Alemtuzumab (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Chronic lymphocytic leukaemia
  • Focus Pharmacogenomic; Therapeutic Use
  • Acronyms HOVON68

Most Recent Events

  • 17 Aug 2023 According to European Clinical Trials Database, the trial is completed in Finland and Czech while its ongoing in Sweden , Denmark and Belgium.
  • 12 Dec 2017 Results (n=187) assessing effect of B-cell receptors stereotypy subsets on the primary outcome presented at the 59th Annual Meeting and Exposition of the American Society of Hematology
  • 14 Jun 2013 Results of an analysis that investigated the effects of genetic mutations on outcomes (n=119) presented at the 18th Congress of the European Haematology Association.

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