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Phase 3, multicenter, multinational, open-label study to evaluate the safety and efficacy of alfimeprase in subjects with occluded central venous access devices (SONOMA-3).

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Trial Profile

Phase 3, multicenter, multinational, open-label study to evaluate the safety and efficacy of alfimeprase in subjects with occluded central venous access devices (SONOMA-3).

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 02 Jun 2011

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At a glance

  • Drugs Alfimeprase (Primary)
  • Indications Catheter thrombosis
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms SONOMA-3
  • Sponsors ARCA biopharma Inc

    • Most Recent Events

    • 12 May 2009 Actual initiation date changed from Feb 2006 to Jan 2006 as reported by ClinicalTrials.gov.
    • 12 May 2009 ClinicalTrials.gov has reported company added as trial sponsor, affiliate and additional lead trial investigator identified.
    • 17 Mar 2008 Results have been reported. Nuvelo's chairman has stated that "[w]e did not see the robust increase in activity or dose resonse expected", and as such, Nuvelo has ended its alfimeprase clinical development program.

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