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A Phase I Study of ZD4054 (Zibotentan) in Combination With Docetaxel in 2 Parts, an Open-Label, Non-Randomized, Dose-Finding Part and a Double-Blind, Placebo-Controlled, Randomized Dose Expansion Part, in Patients With Metastatic Hormone-Refractory Prostate Cancer

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A Phase I Study of ZD4054 (Zibotentan) in Combination With Docetaxel in 2 Parts, an Open-Label, Non-Randomized, Dose-Finding Part and a Double-Blind, Placebo-Controlled, Randomized Dose Expansion Part, in Patients With Metastatic Hormone-Refractory Prostate Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Zibotentan (Primary) ; Docetaxel
  • Indications Prostate cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors AstraZeneca

    • Most Recent Events

    • 21 Nov 2012 New source identified and integrated (German Clinical Trials Register, DRKS00004065).
    • 21 Nov 2012 Planned number of patients changed from 36 to 44 as reported by German Clinical Trials Register record.
    • 01 Sep 2011 Part B results published in Prostate.

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