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Dose intensive chemotherapy for children less than ten years of age newly-diagnosed with malignant brain tumors: a pilot study of two alternative intensive induction chemotherapy regimens, followed by consolidation with myeloablative chemotherapy (thiotepa and carboplatin, with or without etoposide) and autologous stem cell rescue [HEAD START III]

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Dose intensive chemotherapy for children less than ten years of age newly-diagnosed with malignant brain tumors: a pilot study of two alternative intensive induction chemotherapy regimens, followed by consolidation with myeloablative chemotherapy (thiotepa and carboplatin, with or without etoposide) and autologous stem cell rescue [HEAD START III]

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Carboplatin; Cisplatin; Cyclophosphamide; Etoposide; Methotrexate; Temozolomide; Thiotepa; Vincristine
  • Indications Brain cancer
  • Focus Therapeutic Use
  • Acronyms HEAD-START-III

    • Most Recent Events

    • 18 Dec 2013 Biomarkers information updated
    • 20 Oct 2010 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.
    • 21 Oct 2008 Planned end date 1 Dec 2010 added as reported by CT.gov

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