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A randomized, double-blind, placebo controlled, phase IIA study to assess the effect on GERD [gastro-esophageal reflux disease] symptoms, PK [pharmacokinetics], safety and tolerability of 4 weeks treatment with AZD3355 65 mg bid [twice daily] as add-on treatment to a PPI [proton pump inhibitor] in patients with an incomplete response to PPI

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A randomized, double-blind, placebo controlled, phase IIA study to assess the effect on GERD [gastro-esophageal reflux disease] symptoms, PK [pharmacokinetics], safety and tolerability of 4 weeks treatment with AZD3355 65 mg bid [twice daily] as add-on treatment to a PPI [proton pump inhibitor] in patients with an incomplete response to PPI

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Apr 2022

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At a glance

  • Drugs Lesogaberan (Primary) ; Proton pump inhibitors
  • Indications Gastro-oesophageal reflux
  • Focus Therapeutic Use
  • Sponsors AstraZeneca

    • Most Recent Events

    • 18 May 2011 Actual end date (Jun 2007) added as reported by ClinicalTrials.gov.
    • 25 Nov 2009 Primary endpoint 'Clinical response' has been met.
    • 25 Nov 2009 Results reported at Gastro 2009.

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