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A Phase I/II Multicenter, Dose-escalation Study of Oral Nilotinib on a Continuous Daily Dosing Schedule in Adult Patients With Imatinib-resistant or Imatinib-intolerant CML, or Relapse/Refractory Ph+ALL.

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Trial Profile

A Phase I/II Multicenter, Dose-escalation Study of Oral Nilotinib on a Continuous Daily Dosing Schedule in Adult Patients With Imatinib-resistant or Imatinib-intolerant CML, or Relapse/Refractory Ph+ALL.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Nilotinib (Primary)
  • Indications Chronic myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 23 Aug 2011 Actual end date of the extension trial (NCT01279473) is Dec 2009.
    • 23 Aug 2011 Actual end date of the extension trial (NCT01279473) is Dec 2009.
    • 23 Aug 2011 Actual initiation date of the extension trial (NCT01279473) is Aug 2005.

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