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Multicenter, Randomized, Double-Blind, Sham Surgery-Controlled Study of CERE-120 (Adeno-Associated Virus Serotype 2 [AAV2]-Neurturin [NTN]) to Assess the Efficacy and Safety of Bilateral Intraputaminal (IPu) Delivery in Subjects With Idiopathic Parkinson's Disease

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Trial Profile

Multicenter, Randomized, Double-Blind, Sham Surgery-Controlled Study of CERE-120 (Adeno-Associated Virus Serotype 2 [AAV2]-Neurturin [NTN]) to Assess the Efficacy and Safety of Bilateral Intraputaminal (IPu) Delivery in Subjects With Idiopathic Parkinson's Disease

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Nov 2022

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At a glance

  • Drugs CERE 120 (Primary)
  • Indications Parkinson's disease
  • Focus Therapeutic Use
  • Sponsors Ceregene; Sangamo Therapeutics
  • Most Recent Events

    • 20 Oct 2010 Dosing paradigm revised for phase IIb trial (700049522) based on results from this trial, according to Ceregene media release.
    • 27 May 2009 Additional results reported in a Ceregene media release.
    • 08 Apr 2009 Actual initiation date (1 Nov 2006) and lead investigator (Siffert J) added as reported by ClinicalTrials.gov.
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