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A double-blind, double dummy, randomized, parallel group, multi-center, phase III study to evaluate the efficacy and safety of TAK-475 [lapaquistat] alone and TAK-475 administered in combination with ezetimibe versus ezetimibe alone in subjects with primary dyslipidemia.

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Trial Profile

A double-blind, double dummy, randomized, parallel group, multi-center, phase III study to evaluate the efficacy and safety of TAK-475 [lapaquistat] alone and TAK-475 administered in combination with ezetimibe versus ezetimibe alone in subjects with primary dyslipidemia.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 21 Jan 2022

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At a glance

  • Drugs Lapaquistat (Primary) ; Ezetimibe
  • Indications Hypercholesterolaemia
  • Focus Registrational; Therapeutic Use
  • Sponsors Takeda; Takeda Europe Research & Development Centre; Takeda Global Research and Development Center
  • Most Recent Events

    • 28 Mar 2008 Status changed from in progress to discontinued. According to a Takeda media release, development of lapaquistat is being discontinued.
    • 07 Dec 2006 New trial record.

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