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A Phase III, Randomized, Multicenter Trial Comparing Sirolimus/Tacrolimus with Tacrolimus/Methotrexate as Graft-Versus-Host Disease (GVHD) Prophylaxis After HLA-Matched, Related Peripheral Blood Stem Cell Transplantation

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A Phase III, Randomized, Multicenter Trial Comparing Sirolimus/Tacrolimus with Tacrolimus/Methotrexate as Graft-Versus-Host Disease (GVHD) Prophylaxis After HLA-Matched, Related Peripheral Blood Stem Cell Transplantation

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Jan 2023

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At a glance

  • Drugs Methotrexate (Primary) ; Sirolimus (Primary) ; Tacrolimus (Primary)
  • Indications Graft-versus-host disease
  • Focus Therapeutic Use

    • Most Recent Events

    • 04 Dec 2018 Results of post-hoc analysis presented at the 60th Annual Meeting and Exposition of the American Society of Hematology.
    • 06 Dec 2016 Results of biomarker study of endothelial damage and non-relapse mortality presented at the 58th Annual Meeting and Exposition of the American Society of Hematology
    • 08 Feb 2016 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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