A Phase 1/2 Study Of Bosutinib (SKI-606) In Philadelphia Chromosome Positive Leukemias

Trial Profile

A Phase 1/2 Study Of Bosutinib (SKI-606) In Philadelphia Chromosome Positive Leukemias

Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 Jun 2018

At a glance

  • Drugs Bosutinib (Primary)
  • Indications Chronic myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; Pharmacokinetics; Registrational; Therapeutic Use
  • Sponsors Pfizer; Wyeth Pharmaceuticals
  • Most Recent Events

    • 17 Jun 2018 Results assessing cross-intolerance (adverse events leading to discontinuation of both prior TKI and bosutinib) presented at the 23rd Congress of the European Haematology Association
    • 05 Jun 2018 Results of retrospective analysis assessing effects of bosutinib on renal function by using data from two studies including this study published in the Clinical Lymphoma, Myeloma & Leukemia.
    • 12 Dec 2017 Long-term results of cardiac, vascular and hypertensive safety of bosutinib from parent and extension studies presented at the 59th Annual Meeting and Exposition of the American Society of Hematology
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