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A Phase III Randomized Study of Cetuximab +/- Brivanib Alaninate (BMS-582664) in Patients With K-RAS Wild Type Tumors Previously Treated With Combination Chemotherapy for Metastatic Colorectal Carcinoma

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Trial Profile

A Phase III Randomized Study of Cetuximab +/- Brivanib Alaninate (BMS-582664) in Patients With K-RAS Wild Type Tumors Previously Treated With Combination Chemotherapy for Metastatic Colorectal Carcinoma

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 08 Jan 2024

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At a glance

  • Drugs Brivanib alaninate (Primary) ; Cetuximab
  • Indications Colorectal cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 03 Jan 2024 Results of pooled analysis from CO.17 and CO.20 investigating transverse colon primary tumor location as a biomarker in mCRC, published in the Clinical Cancer Research
    • 21 Jan 2023 Results of pooled analysis of two studies (CO.17 and CO.20) assessing the predictive and prognostic features of transverse colon primary location, presented at the 2023 Gastrointestinal Cancers Symposium.
    • 20 Jan 2018 Results assessing the association of FCGR2A and FCGR3A polymorphisms with outcomes in cetuximab treated patients (n=592) presented at the 2018 Gastrointestinal Cancers Symposium

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