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A Randomized, Open-Label, Comparative 3-Way Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40 mg, Lansoprazole 30 mg, and Pantoprazole 40 mg at Steady State in Hispanic Patients With Symptomatic GERD [gastro-oesophageal reflux disease]

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Trial Profile

A Randomized, Open-Label, Comparative 3-Way Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40 mg, Lansoprazole 30 mg, and Pantoprazole 40 mg at Steady State in Hispanic Patients With Symptomatic GERD [gastro-oesophageal reflux disease]

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 05 Jun 2010

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At a glance

  • Drugs Esomeprazole (Primary) ; Lansoprazole (Primary) ; Pantoprazole (Primary)
  • Indications Gastro-oesophageal reflux
  • Focus Pharmacodynamics
  • Sponsors AstraZeneca
  • Most Recent Events

    • 23 Apr 2010 Primary endpoint 'Time with intragastric pH greater than 4' has been met.
    • 23 Apr 2010 Results published in Alimentary Pharmacology and Therapeutics.
    • 28 Oct 2008 Results have been reported at the 73rd Annual Scientific Meeting of the American College of Gastroenterology.

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