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Phase III Randomized Study of the Effects on Bone Mineral Density of Tamoxifen, Letrozole, and Letrozole + Zoledronic Acid as Adjuvant Treatment of Patients With Early Breast Cancer; VERSION 2 AMENDED Phase 3 Study of Triptorelin and Tamoxifen, Letrozole, or Letrozole + Zoledronic Acid in Adjuvant Treatment of Premenopausal Endocrine Responsive Breast Cancer Patients.

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Trial Profile

Phase III Randomized Study of the Effects on Bone Mineral Density of Tamoxifen, Letrozole, and Letrozole + Zoledronic Acid as Adjuvant Treatment of Patients With Early Breast Cancer; VERSION 2 AMENDED Phase 3 Study of Triptorelin and Tamoxifen, Letrozole, or Letrozole + Zoledronic Acid in Adjuvant Treatment of Premenopausal Endocrine Responsive Breast Cancer Patients.

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 06 Mar 2023

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At a glance

  • Drugs Letrozole (Primary) ; Triptorelin (Primary) ; Zoledronic acid (Primary) ; Tamoxifen
  • Indications Early breast cancer; Osteoporosis
  • Focus Therapeutic Use
  • Acronyms HOBOE
  • Most Recent Events

    • 06 Mar 2023 According to ClinicalTrials.gov, the recruitment status of this study is unknown because the information has not been verified recently (last verified March 2021).
    • 03 Mar 2021 Planned End Date changed from 1 Mar 2019 to 1 Nov 2022.
    • 03 Mar 2021 Planned primary completion date changed from 1 Mar 2018 to 1 Nov 2021.
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