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A multicenter randomized open label study to assess efficacy and safety of a steroids avoidance regimen in comparison to a treatment with steroids, in combination with enteric-coated mycophenolate sodium (EC-MPS) 2.16 g/d for 6 weeks and cyclosporine microemulsion, in de novo adult renal transplant recipients

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Trial Profile

A multicenter randomized open label study to assess efficacy and safety of a steroids avoidance regimen in comparison to a treatment with steroids, in combination with enteric-coated mycophenolate sodium (EC-MPS) 2.16 g/d for 6 weeks and cyclosporine microemulsion, in de novo adult renal transplant recipients

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Mycophenolate sodium (Primary) ; Ciclosporin; Prednisone
  • Indications Renal transplant rejection
  • Focus Therapeutic Use
  • Acronyms DOMINOS
  • Sponsors Novartis
  • Most Recent Events

    • 15 Aug 2010 Results presented at the 23rd International Congress of the Transplantation Society.
    • 04 May 2010 Results have been presented at the American Transplant Congress.
    • 10 Nov 2009 Planned number of patients changed from 210 to 220 as reported by ClinicalTrials.gov.
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