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A Phase III, Randomized, Double-blinded, Parallel Group, Multi-centre Study to Assess the Efficacy and Safety of ZD6474 (ZACTIMA) in Combination With Pemetrexed (Alimta) Versus Pemetrexed Alone in Patients With Locally-Advanced or Metastatic NSCLC

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A Phase III, Randomized, Double-blinded, Parallel Group, Multi-centre Study to Assess the Efficacy and Safety of ZD6474 (ZACTIMA) in Combination With Pemetrexed (Alimta) Versus Pemetrexed Alone in Patients With Locally-Advanced or Metastatic NSCLC

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 04 Jan 2025

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At a glance

  • Drugs Vandetanib (Primary) ; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ZEAL
  • Sponsors AstraZeneca; Sanofi Genzyme

    • Most Recent Events

    • 19 Sep 2023 Status changed from active, no longer recruiting to completed.
    • 03 Oct 2022 Planned End Date changed from 31 Dec 2022 to 29 Dec 2023.
    • 20 Oct 2021 Planned End Date changed from 30 Dec 2020 to 31 Dec 2022.

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