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To define in human preclinical systolic dysfunction (PSD) the actions of chronic administration of SQ BNP [nesiritide] on the left ventricular, renal and humoral function and on the integrated response to acute sodium loading.

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Trial Profile

To define in human preclinical systolic dysfunction (PSD) the actions of chronic administration of SQ BNP [nesiritide] on the left ventricular, renal and humoral function and on the integrated response to acute sodium loading.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 12 May 2014

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At a glance

  • Drugs Nesiritide (Primary)
  • Indications Heart failure
  • Focus Pharmacodynamics

    • Most Recent Events

    • 16 Mar 2014 Primary endpoint and the number of arms (1 to 2) has been changed as reported by ClinicalTrials.gov record.
    • 20 Nov 2013 Results presented at the 86th Annual Scientific Sessions of the American Heart Association.
    • 20 Nov 2013 Status changed from active, no longer recruiting to completed.

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