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Letrozole Versus Letrozole Plus Lapatinib (GW572016) in Hormone-sensitive, HER-2 Negative Operable Breast Cancer. A Double Blind Randomized Phase II Study With Biomarker Evaluation.

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Trial Profile

Letrozole Versus Letrozole Plus Lapatinib (GW572016) in Hormone-sensitive, HER-2 Negative Operable Breast Cancer. A Double Blind Randomized Phase II Study With Biomarker Evaluation.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Sep 2023

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At a glance

  • Drugs Lapatinib (Primary) ; Letrozole
  • Indications Early breast cancer; HER2 negative breast cancer
  • Focus Biomarker; Therapeutic Use
  • Acronyms LET-LOB
  • Sponsors GlaxoSmithKline
  • Most Recent Events

    • 04 Jun 2013 Biomarker results presented at the 49th Annual Meeting of the American Society of Clinical Oncology.
    • 06 Jul 2011 Preliminary results have been reported at ASCO 2011.
    • 01 Apr 2011 Primary endpoint 'Objective-clinical-response-rate' has not been met.
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