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A Randomized, Double-Blind Placebo-Controlled, Multicenter Phase III Study in Patients With Advanced Carcinoid Tumor Receiving Octreotide Depot and Everolimus 10 mg/Day or Octreotide Depot and Placebo

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Trial Profile

A Randomized, Double-Blind Placebo-Controlled, Multicenter Phase III Study in Patients With Advanced Carcinoid Tumor Receiving Octreotide Depot and Everolimus 10 mg/Day or Octreotide Depot and Placebo

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 20 Jan 2022

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At a glance

  • Drugs Everolimus (Primary) ; Octreotide (Primary)
  • Indications Carcinoid tumour; Neuroendocrine tumours
  • Focus Registrational; Therapeutic Use
  • Acronyms RADIANT-2
  • Sponsors Novartis; Novartis Pharmaceuticals

Most Recent Events

  • 24 Apr 2017 Results of open-label extension phase (n=170) published in the Annals of Oncology
  • 07 Nov 2016 Results of a pharmacokinetic analysis published in the Clinical Pharmacology and Therapeutics
  • 03 Jun 2014 Pooled analysis assessing incidence of stomatitis and correlation with efficacy presented at the 50th Annual Meeting of the American Society of Clinical Oncology.

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