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A Randomized Phase III Study Comparing Epirubicin, Docetaxel and Capecitabine + G-CSF to Epirubicin and Docetaxel + G-CSF as Neoadjuvant Treatment for Early HER-2 Negative Breast Cancer and Comparing Epirubicin, Docetaxel and Capecitabine + G-CSF ± Trastuzumab to Epirubicin and Docetaxel + G-CSF ± Trastuzumab as Neoadjuvant Treatment for Early HER-2 Positive Breast Cancer.

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A Randomized Phase III Study Comparing Epirubicin, Docetaxel and Capecitabine + G-CSF to Epirubicin and Docetaxel + G-CSF as Neoadjuvant Treatment for Early HER-2 Negative Breast Cancer and Comparing Epirubicin, Docetaxel and Capecitabine + G-CSF ± Trastuzumab to Epirubicin and Docetaxel + G-CSF ± Trastuzumab as Neoadjuvant Treatment for Early HER-2 Positive Breast Cancer.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 15 Feb 2022

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At a glance

  • Drugs Capecitabine (Primary) ; Trastuzumab (Primary) ; Docetaxel; Epirubicin; Filgrastim; Lenograstim; Pegfilgrastim
  • Indications Early breast cancer; HER2 negative breast cancer; HER2 positive breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 14 Dec 2019 Results (N= 15,457), a metanalysis of prospective randomized trials assessing efficacy of Capecitabine as a part of neo adjuvant or adjuvant therapy in patients with early breast cancer, presented at the 42nd Annual San Antonio Breast Cancer Symposium
    • 16 Dec 2013 Results published in the Annals of Oncology.
    • 29 Dec 2011 Official title amended as reported by ClinicalTrials.gov.

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