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A phase IB, open label, single center, drug-drug interaction study of oral 1250 mg of PTK787/ZK 222584 [vatalanib] administered under fasting and fed conditions with a proton-pump inhibitor (omeprazole) in healthy sterile or postmenopausal female volunteers.

Trial Profile

A phase IB, open label, single center, drug-drug interaction study of oral 1250 mg of PTK787/ZK 222584 [vatalanib] administered under fasting and fed conditions with a proton-pump inhibitor (omeprazole) in healthy sterile or postmenopausal female volunteers.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 01 Oct 2009

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At a glance

  • Drugs Vatalanib (Primary) ; Omeprazole
  • Indications Age-related macular degeneration; Colorectal cancer; Gastro-oesophageal reflux; Glioblastoma; Multiple myeloma; Non-small cell lung cancer; Ovarian cancer; Renal cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Novartis

Most Recent Events

  • 17 Feb 2007 New trial record.

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